{"id":6221,"date":"2026-06-10T12:00:22","date_gmt":"2026-06-10T03:00:22","guid":{"rendered":"https:\/\/cm-plus.co.jp\/vn\/?post_type=column&p=6221"},"modified":"2026-07-02T09:40:40","modified_gmt":"2026-07-02T00:40:40","slug":"2026_0610","status":"publish","type":"column","link":"https:\/\/cm-plus.co.jp\/vn\/column\/gmp\/2026_0610\/","title":{"rendered":"\u0110\u1ea1i c\u01b0\u01a1ng v\u1ec1 Vi sinh h\u1ecdc [Ph\u1ea7n 1]"},"content":{"rendered":"

B\u00e0i vi\u1ebft n\u00e0y l\u00e0 phi\u00ean b\u1ea3n c\u1eadp nh\u1eadt m\u1edbi nh\u1ea5t n\u0103m 2026 c\u1ee7a chu\u1ed7i chuy\u00ean \u0111\u1ec1 50 k\u1ef3 v\u00f4 c\u00f9ng n\u1ed5i ti\u1ebfng t\u1ea1i Nh\u1eadt B\u1ea3n mang t\u00ean: \u201cVi sinh v\u1eadt: Chuy\u1ec7n ch\u01b0a k\u1ec3 v\u00e0 nh\u1eefng \u0111i\u1ec1u \u2018ng\u1ea1i\u2019 h\u1ecfi!\u201d (\u3044\u307e\u3055\u3089\u4eba\u306b\u306f\u805e\u3051\u306a\u3044\uff01\u5fae\u751f\u7269\u306e\u304a\u8a71), t\u1eebng \u0111\u01b0\u1ee3c xu\u1ea5t b\u1ea3n tr\u01b0\u1edbc \u0111\u00f3 tr\u00ean chuy\u00ean trang GMP Platform*.<\/p>\n

Trong c\u00e1c k\u1ef3 t\u1edbi c\u1ee7a lo\u1ea1t b\u00e0i n\u00e0y, t\u00f4i s\u1ebd c\u00f9ng qu\u00fd \u0111\u1ed9c gi\u1ea3 kh\u00e1m ph\u00e1 m\u1ed9t l\u0103ng k\u00ednh to\u00e0n di\u1ec7n v\u00e0 \u0111a d\u1ea1ng v\u1ec1 th\u1ebf gi\u1edbi vi sinh v\u1eadt \u2014 \u0111i t\u1eeb nh\u1eefng ki\u1ebfn th\u1ee9c \u0111\u1ea1i c\u01b0\u01a1ng c\u01a1 b\u1ea3n nh\u1ea5t cho \u0111\u1ebfn nh\u1eefng g\u00f3c nh\u00ecn chuy\u00ean s\u00e2u, nh\u1eefng b\u00ed m\u1eadt ngh\u1ec1 nghi\u1ec7p m\u00e0 ngay c\u1ea3 c\u00e1c chuy\u00ean gia l\u00e2u n\u0103m trong ng\u00e0nh c\u0169ng ch\u01b0a ch\u1eafc \u0111\u00e3 t\u01b0\u1eddng t\u1eadn.<\/p>\n

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Vi sinh v\u1eadt: \u0110\u1ea1i c\u01b0\u01a1ng v\u1ec1 nh\u1eefng nguy\u00ean l\u00fd c\u01a1 b\u1ea3n<\/strong><\/span><\/p>\n

Tr\u00e1i \u0110\u1ea5t \u0111\u01b0\u1ee3c h\u00ecnh th\u00e0nh c\u00e1ch \u0111\u00e2y kho\u1ea3ng 4,6 t\u1ef7 n\u0103m, v\u00e0 s\u1ef1 s\u1ed1ng nguy\u00ean th\u1ee7y \u0111\u01b0\u1ee3c cho l\u00e0 \u0111\u00e3 xu\u1ea5t hi\u1ec7n kho\u1ea3ng 600 tri\u1ec7u n\u0103m sau \u0111\u00f3, t\u1ee9c l\u00e0 c\u00e1ch \u0111\u00e2y kho\u1ea3ng 4 t\u1ef7 n\u0103m. S\u1ef1 s\u1ed1ng th\u1eddi k\u1ef3 \u0111\u1ea7u ho\u00e0n to\u00e0n kh\u00f4ng ph\u1ee9c t\u1ea1p; ch\u00fang \u0111\u01b0\u1ee3c cho l\u00e0 c\u00e1c sinh v\u1eadt \u0111\u01a1n b\u00e0o \u2014 t\u1ee9c l\u00e0 c\u00e1c vi sinh v\u1eadt \u2014 c\u00f3 kh\u1ea3 n\u0103ng ch\u1ed1ng ch\u1ecbu v\u1edbi m\u00f4i tr\u01b0\u1eddng kh\u1eafc nghi\u1ec7t th\u1eddi b\u1ea5y gi\u1edd. M\u1eb7c d\u00f9 c\u00f3 nhi\u1ec1u gi\u1ea3 thuy\u1ebft kh\u00e1c nhau, nh\u01b0ng lo\u00e0i ng\u01b0\u1eddi m\u1edbi ch\u1ec9 xu\u1ea5t hi\u1ec7n tr\u00ean Tr\u00e1i \u0110\u1ea5t c\u00e1ch \u0111\u00e2y v\u00e0i tr\u0103m ngh\u00ecn n\u0103m. N\u00f3i c\u00e1ch kh\u00e1c, x\u00e9t v\u1ec1 t\u01b0 c\u00e1ch l\u00e0 nh\u1eefng sinh v\u1eadt s\u1ed1ng tr\u00ean Tr\u00e1i \u0110\u1ea5t, vi sinh v\u1eadt ch\u00ednh l\u00e0 “b\u1eadc ti\u1ec1n b\u1ed1i” c\u1ee7a con ng\u01b0\u1eddi.<\/p>\n

Ng\u00e0y nay, s\u1ef1 t\u1ed3n t\u1ea1i c\u1ee7a c\u00e1c sinh v\u1eadt v\u00f4 c\u00f9ng nh\u1ecf b\u00e9 kh\u00f4ng th\u1ec3 nh\u00ecn th\u1ea5y b\u1eb1ng m\u1eaft th\u01b0\u1eddng \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 vi sinh v\u1eadt \u0111\u00e3 l\u00e0 m\u1ed9t th\u1ef1c t\u1ebf r\u00f5 r\u00e0ng. Ch\u00fang ta c\u0169ng bi\u1ebft r\u1ea5t r\u00f5 r\u1eb1ng ch\u00fang c\u00f3 th\u1ec3 g\u00e2y b\u1ec7nh, l\u00e0m h\u01b0 h\u1ecfng th\u1ef1c ph\u1ea9m, ho\u1eb7c t\u1ea1o ra c\u00e1c ch\u1ea5t c\u00f3 h\u1ea1i\/c\u00f3 \u00edch th\u00f4ng qua m\u1ed9t qu\u00e1 tr\u00ecnh g\u1ecdi l\u00e0 l\u00ean men. Nh\u1eefng hi\u1ec7n t\u01b0\u1ee3ng do vi sinh v\u1eadt g\u00e2y ra nh\u01b0 v\u1eady \u0111\u00e3 \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn t\u1eeb th\u1eddi c\u1ed5 \u0111\u1ea1i. C\u00e1c c\u0103n b\u1ec7nh do vi sinh v\u1eadt g\u00e2y ra \u2014 t\u1ee9c l\u00e0 b\u1ec7nh truy\u1ec1n nhi\u1ec5m \u2014 \u0111\u00e3 t\u1ed3n t\u1ea1i t\u1eeb tr\u01b0\u1edbc khi con ng\u01b0\u1eddi sinh ra, v\u00e0 t\u1ed5 ti\u00ean c\u1ee7a ch\u00fang ta ch\u1eafc ch\u1eafn \u0111\u00e3 ph\u1ea3i tr\u1ea3i qua nh\u1eefng cu\u1ed9c chi\u1ebfn ch\u1ed1ng l\u1ea1i c\u00e1c c\u0103n b\u1ec7nh truy\u1ec1n nhi\u1ec5m n\u00e0y. M\u1ed9t \u0111i\u1ec1u hi\u1ec3n nhi\u00ean l\u00e0 th\u1ef1c ph\u1ea9m s\u1ebd b\u1ecb h\u01b0 h\u1ecfng n\u1ebfu kh\u00f4ng \u0111\u01b0\u1ee3c b\u1ea3o qu\u1ea3n, v\u00e0 nhi\u1ec1u c\u00f4ng ngh\u1ec7 ch\u1ebf bi\u1ebfn kh\u00e1c nhau nh\u01b0 s\u1ea5y kh\u00f4 hay mu\u1ed1i chua \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n \u0111\u1ec3 ng\u0103n ch\u1eb7n s\u1ef1 h\u01b0 h\u1ecfng n\u00e0y. R\u01b0\u1ee3u v\u00e0 gi\u1ea5m c\u0169ng \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1eb1ng qu\u00e1 tr\u00ecnh l\u00ean men vi sinh, v\u00e0 ng\u01b0\u1eddi ta n\u00f3i r\u1eb1ng ch\u00fang \u0111\u00e3 \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn t\u1eeb h\u00e0ng ng\u00e0n n\u0103m tr\u01b0\u1edbc. Nh\u1eefng \u0111i\u1ec1u n\u00e0y \u0111\u00e3 \u0111\u01b0\u1ee3c ghi nh\u1eadn v\u00e0 l\u01b0u truy\u1ec1n l\u1ea1i theo kinh nghi\u1ec7m th\u1ef1c t\u1ebf, nh\u01b0ng lo\u00e0i ng\u01b0\u1eddi \u0111\u00e3 kh\u00f4ng h\u1ec1 nh\u1eadn th\u1ee9c \u0111\u01b0\u1ee3c r\u1eb1ng c\u00e1c hi\u1ec7n t\u01b0\u1ee3ng n\u00e0y l\u00e0 do nh\u1eefng sinh m\u1ec7nh nh\u1ecf b\u00e9 \u2014 t\u1ee9c l\u00e0 vi sinh v\u1eadt \u2014 g\u00e2y ra cho \u0111\u1ebfn t\u1eadn gi\u1eefa nh\u1eefng n\u0103m 1800. V\u00e0 k\u1ec3 t\u1eeb nh\u1eefng n\u0103m 1970, vi sinh h\u1ecdc \u0111\u00e3 ph\u00e1t tri\u1ec3n v\u01b0\u1ee3t b\u1eadc th\u00e0nh m\u1ed9t ng\u00e0nh c\u00f4ng ngh\u1ec7 ti\u00ean ti\u1ebfn \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 C\u00f4ng ngh\u1ec7 sinh h\u1ecdc<\/p>\n

Vi sinh v\u1eadt l\u00e0 nh\u1eefng sinh v\u1eadt s\u1ed1ng. Do \u0111\u00f3, ch\u00fang s\u1edf h\u1eefu c\u00e1c \u0111\u1eb7c t\u00ednh sinh h\u1ecdc nh\u01b0 qu\u00e1 tr\u00ecnh trao \u0111\u1ed5i ch\u1ea5t ho\u1eb7c kh\u1ea3 n\u0103ng sinh s\u1ea3n. Ch\u00fa th\u00edch)<\/sup><\/em> Tuy nhi\u00ean, \u0111\u00fang nh\u01b0 t\u00ean g\u1ecdi c\u1ee7a m\u00ecnh, vi sinh v\u1eadt c\u00f3 k\u00edch th\u01b0\u1edbc c\u1ef1c k\u1ef3 nh\u1ecf b\u00e9, v\u00ec v\u1eady ch\u00fang ta kh\u00f4ng th\u1ec3 quan s\u00e1t chi ti\u1ebft c\u1ea5u t\u1ea1o c\u1ee7a ch\u00fang b\u1eb1ng m\u1eaft th\u01b0\u1eddng. \u0110\u1ec3 quan s\u00e1t \u0111\u01b0\u1ee3c, vi\u1ec7c s\u1eed d\u1ee5ng k\u00ednh hi\u1ec3n vi l\u00e0 \u0111i\u1ec1u b\u1eaft bu\u1ed9c.<\/p>\n

Ch\u00fa th\u00edch) Qu\u00e1 tr\u00ecnh trao \u0111\u1ed5i ch\u1ea5t hay kh\u1ea3 n\u0103ng sinh s\u1ea3n, v\u1ed1n l\u00e0 nh\u1eefng \u0111\u1eb7c t\u00ednh chung c\u1ee7a sinh v\u1eadt s\u1ed1ng, \u0111\u1ec1u \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y m\u1ed9t c\u00e1ch ph\u1ed5 bi\u1ebfn t\u1eeb c\u00e1c sinh v\u1eadt \u0111\u01a1n b\u00e0o nh\u01b0 vi khu\u1ea9n cho \u0111\u1ebfn c\u00e1c sinh v\u1eadt b\u1eadc cao nh\u01b0 \u0111\u1ed9ng v\u1eadt c\u00f3 v\u00fa. Tuy nhi\u00ean, kh\u00f4ng th\u1ec3 n\u00f3i r\u1eb1ng virus hay c\u00e1c prion “s\u1edf h\u1eefu c\u00e1c \u0111\u1eb7c t\u00ednh sinh h\u1ecdc” n\u00e0y. Do \u0111\u00f3, trong c\u00e1c cu\u1ed9c th\u1ea3o lu\u1eadn \u0111\u1ecbnh ngh\u0129a m\u1ed9t c\u00e1ch nghi\u00eam ng\u1eb7t v\u1ec1 “sinh v\u1eadt s\u1ed1ng”, c\u00e1ch di\u1ec5n \u0111\u1ea1t tr\u00ean c\u00f3 th\u1ec3 ch\u01b0a ho\u00e0n to\u00e0n ch\u00ednh x\u00e1c. M\u1eb7c d\u00f9 v\u1eady, v\u00ec b\u00e0i vi\u1ebft n\u00e0y d\u00e0nh cho nh\u1eefng ng\u01b0\u1eddi m\u1edbi b\u1eaft \u0111\u1ea7u t\u00ecm hi\u1ec3u v\u1ec1 vi sinh h\u1ecdc, n\u00ean t\u00ednh d\u1ec5 hi\u1ec3u s\u1ebd \u0111\u01b0\u1ee3c \u01b0u ti\u00ean h\u00e0ng \u0111\u1ea7u. V\u00ec v\u1eady, m\u1ed9t s\u1ed1 ngo\u1ea1i l\u1ec7 c\u00f3 th\u1ec3 s\u1ebd t\u1ed3n t\u1ea1i trong m\u1ed9t v\u00e0i ph\u1ea7n m\u00f4 t\u1ea3.<\/em>.<\/em><\/p>\n

AM\u1eb7c d\u00f9 kh\u00f4ng c\u00f3 \u0111\u1ecbnh ngh\u0129a n\u00e0o ho\u00e0n to\u00e0n r\u00f5 r\u00e0ng cho thu\u1eadt ng\u1eef “vi sinh v\u1eadt”, nh\u01b0ng n\u00f3 th\u01b0\u1eddng \u0111\u01b0\u1ee3c hi\u1ec3u l\u00e0 “m\u1ed9t sinh v\u1eadt hi\u1ec3n vi c\u00f3 c\u1ea5u tr\u00fac kh\u00f4ng th\u1ec3 ph\u00e2n bi\u1ec7t \u0111\u01b0\u1ee3c b\u1eb1ng m\u1eaft th\u01b0\u1eddng” (theo Wikipedia). V\u1eady m\u1ed9t sinh v\u1eadt ph\u1ea3i nh\u1ecf \u0111\u1ebfn m\u1ee9c n\u00e0o th\u00ec m\u1edbi \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 vi sinh v\u1eadt? K\u00edch th\u01b0\u1edbc “kh\u00f4ng th\u1ec3 ph\u00e2n bi\u1ec7t \u0111\u01b0\u1ee3c b\u1eb1ng m\u1eaft th\u01b0\u1eddng” l\u00e0 bao nhi\u00eau? Do c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t l\u1edbn gi\u1eefa t\u1eebng c\u00e1 th\u1ec3, ch\u00fang ta kh\u00f4ng th\u1ec3 v\u1ea1ch ra m\u1ed9t ranh gi\u1edbi r\u00f5 r\u00e0ng, nh\u01b0ng m\u1ed9t s\u1ed1 t\u00e0i li\u1ec7u \u0111\u00e3 \u0111\u01b0a ra con s\u1ed1 x\u1ea5p x\u1ec9 0,1 mm \u0111\u1ec3 ch\u1ec9 \u0111\u1ed9 ph\u00e2n gi\u1ea3i c\u1ee7a m\u1eaft ng\u01b0\u1eddi (kho\u1ea3ng c\u00e1ch t\u1ed1i thi\u1ec3u m\u00e0 t\u1ea1i \u0111\u00f3 hai \u0111i\u1ec3m c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c nh\u1eadn bi\u1ebft l\u00e0 t\u00e1ch bi\u1ec7t nhau). IN\u00f3i m\u1ed9t c\u00e1ch \u0111\u01a1n gi\u1ea3n, n\u1ebfu k\u00edch th\u01b0\u1edbc t\u1eeb kho\u1ea3ng 0,1 mm tr\u1edf xu\u1ed1ng, \u0111i\u1ec1u \u0111\u00f3 c\u00f3 ngh\u0129a l\u00e0 “kh\u00f4ng th\u1ec3 quan s\u00e1t chi ti\u1ebft b\u1eb1ng m\u1eaft th\u01b0\u1eddng” = “vi sinh v\u1eadt”. V\u1eady c\u1ee5 th\u1ec3 th\u00ec 0,1 mm nh\u1ecf nh\u01b0 th\u1ebf n\u00e0o? N\u00f3 b\u1eb1ng 1\/10 c\u1ee7a v\u1ea1ch chia 1 mm tr\u00ean th\u01b0\u1edbc k\u1ebb n\u00ean r\u1ea5t d\u1ec5 h\u00ecnh dung, nh\u01b0ng \u0111\u1ec3 \u0111\u01b0a ra m\u1ed9t v\u00ed d\u1ee5 c\u1ee5 th\u1ec3, \u0111\u1ed9 d\u00e0y c\u1ee7a gi\u1ea5y photo th\u00f4ng th\u01b0\u1eddng l\u00e0 0,09 mm, v\u00e0 \u0111\u1ed9 d\u00e0y trung b\u00ecnh c\u1ee7a m\u1ed9t s\u1ee3i t\u00f3c ng\u01b0\u1eddi Nh\u1eadt \u0111\u01b0\u1ee3c cho l\u00e0 kho\u1ea3ng 0,07 mm. \u0110\u00e2y l\u00e0 nh\u1eefng k\u00edch th\u01b0\u1edbc ho\u00e0n to\u00e0n c\u00f3 th\u1ec3 nh\u00ecn th\u1ea5y \u0111\u01b0\u1ee3c b\u1eb1ng m\u1eaft th\u01b0\u1eddng, nh\u01b0ng th\u00f4ng th\u01b0\u1eddng ch\u00fang ta kh\u00f4ng th\u1ec3 quan s\u00e1t chi ti\u1ebft m\u1eb7t c\u1eaft ngang c\u1ee7a t\u1edd gi\u1ea5y hay tr\u1ea1ng th\u00e1i c\u1ee7a m\u1ed9t s\u1ee3i t\u00f3c \u0111\u01a1n l\u1ebb b\u1eb1ng m\u1eaft th\u01b0\u1eddng \u0111\u01b0\u1ee3c. \u0110\u00e2y \u0111\u01b0\u1ee3c coi l\u00e0 gi\u1edbi h\u1ea1n th\u00f4 cho \u0111\u1ed9 ph\u00e2n gi\u1ea3i c\u1ee7a m\u1eaft ng\u01b0\u1eddi tr\u1ea7n.<\/p>\n

Do \u0111\u00f3, c\u00f3 th\u1ec3 n\u00f3i m\u1ed9t c\u00e1ch \u0111\u01a1n gi\u1ea3n r\u1eb1ng “c\u00e1c sinh v\u1eadt nh\u1ecf h\u01a1n \u0111\u1ed9 d\u00e0y c\u1ee7a m\u1ed9t s\u1ee3i t\u00f3c l\u00e0 vi sinh v\u1eadt”, nh\u01b0ng nh\u00ecn chung, c\u00e1c sinh v\u1eadt \u0111\u01a1n b\u00e0o c\u00f3 k\u00edch th\u01b0\u1edbc nh\u1ecf h\u01a1n th\u1ebf m\u1ed9t b\u1eadc (m\u1ed9t c\u1ea5p \u0111\u1ed9 ph\u00e2n t\u1eed) m\u1edbi \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 vi sinh v\u1eadt. Nh\u00f3m n\u00e0y bao g\u1ed3m vi n\u1ea5m (n\u1ea5m men ho\u1eb7c n\u1ea5m m\u1ed1c), vi khu\u1ea9n (nh\u01b0 E. coli ho\u1eb7c S. aureus), v\u00e0 th\u1eadm ch\u00ed c\u1ea3 c\u00e1c mycoplasma ho\u1eb7c virus c\u00f3 k\u00edch th\u01b0\u1edbc c\u00f2n nh\u1ecf h\u01a1n n\u1eefa.<\/p>\n

Nh\u01b0 v\u1eady, vi sinh v\u1eadt th\u1ef1c ch\u1ea5t l\u00e0 m\u1ed9t thu\u1eadt ng\u1eef g\u1ecdi chung d\u1ef1a tr\u00ean k\u00edch th\u01b0\u1edbc si\u00eau nh\u1ecf, ch\u1ee9 kh\u00f4ng ph\u1ea3i l\u00e0 m\u1ed9t nh\u00f3m sinh v\u1eadt \u0111\u1ed3ng nh\u1ea5t v\u1ec1 m\u1eb7t sinh h\u1ecdc. \u0110i\u1ec3m chung duy nh\u1ea5t gi\u1eefa ch\u00fang l\u00e0 k\u00edch th\u01b0\u1edbc “nh\u1ecf b\u00e9”, nh\u01b0ng c\u00e1c \u0111\u1eb7c t\u00ednh sinh h\u1ecdc l\u1ea1i c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t v\u00f4 c\u00f9ng l\u1edbn.<\/p>\n

\u0110\u1ec3 gi\u00fap qu\u00fd \u0111\u1ed9c gi\u1ea3 v\u00e0 c\u00e1c k\u1ef9 thu\u1eadt vi\u00ean c\u00f3 c\u00e1i nh\u00ecn t\u1ed5ng quan, B\u1ea3ng 1-1 d\u01b0\u1edbi \u0111\u00e2y s\u1ebd t\u00f3m t\u1eaft nh\u1eefng \u0111i\u1ec3m kh\u00e1c bi\u1ec7t c\u1ed1t l\u00f5i gi\u1eefa c\u00e1c nh\u00f3m sinh v\u1eadt ph\u1ed5 bi\u1ebfn, bao g\u1ed3m c\u00e1c vi sinh v\u1eadt \u0111i\u1ec3n h\u00ecnh nh\u01b0 vi khu\u1ea9n, vi n\u1ea5m, cho \u0111\u1ebfn c\u00e1c t\u00e1c nh\u00e2n \u0111\u1eb7c bi\u1ec7t nh\u01b0 virus, mycoplasma v\u00e0 rickettsia.<\/p>\n

\"\"

B\u1ea3ng 1-1: Nh\u1eefng \u0111i\u1ec3m kh\u00e1c bi\u1ec7t c\u1ed1t l\u00f5i gi\u1eefa c\u00e1c nh\u00f3m sinh v\u1eadt ph\u1ed5 bi\u1ebfn N\u1ed9i dung \u0111\u01b0\u1ee3c hi\u1ec7u \u0111\u00ednh v\u00e0 tr\u00edch d\u1eabn m\u1ed9t ph\u1ea7n t\u1eeb… https:\/\/ja.wikipedia.org\/wiki\/\u30a6\u30a4\u30eb\u30b9<\/p><\/div>\n

V\u00ec vi sinh v\u1eadt c\u00f3 k\u00edch th\u01b0\u1edbc si\u00eau nh\u1ecf, vi\u1ec7c s\u1eed d\u1ee5ng k\u00ednh hi\u1ec3n vi l\u00e0 \u0111i\u1ec1u b\u1eaft bu\u1ed9c \u0111\u1ec3 c\u00f3 th\u1ec3 quan s\u00e1t \u0111\u01b0\u1ee3c ch\u00fang. \u0110\u1ed1i v\u1edbi vi khu\u1ea9n v\u00e0 vi n\u1ea5m, ch\u00fang ta c\u00f3 th\u1ec3 d\u1ec5 d\u00e0ng quan s\u00e1t b\u1eb1ng k\u00ednh hi\u1ec3n vi quang h\u1ecdc (k\u00ednh hi\u1ec3n vi sinh h\u1ecdc th\u00f4ng th\u01b0\u1eddng). Tuy nhi\u00ean, virus l\u1ea1i c\u00f3 k\u00edch th\u01b0\u1edbc nh\u1ecf h\u01a1n r\u1ea5t nhi\u1ec1u, \u0111\u00f2i h\u1ecfi ph\u1ea3i s\u1eed d\u1ee5ng k\u00ednh hi\u1ec3n vi \u0111i\u1ec7n t\u1eed m\u1edbi c\u00f3 th\u1ec3 nh\u00ecn th\u1ea5y c\u1ea5u tr\u00fac c\u1ee7a ch\u00fang.<\/p>\n

Khi ch\u00fang ta \u0111\u1eb7t t\u1ea5t c\u1ea3 c\u00e1c sinh v\u1eadt (bao g\u1ed3m c\u1ea3 vi sinh v\u1eadt) l\u00ean m\u1ed9t tr\u1ee5c \u0111o l\u01b0\u1eddng v\u1edbi k\u00edch th\u01b0\u1edbc l\u00e0 th\u01b0\u1edbc \u0111o ch\u1ec9 th\u1ecb, t\u01b0\u01a1ng quan v\u1ec1 \u0111\u1ed9 l\u1edbn gi\u1eefa c\u00e1c nh\u00f3m s\u1ebd \u0111\u01b0\u1ee3c th\u1ec3 hi\u1ec7n m\u1ed9t c\u00e1ch tr\u1ef1c quan nh\u01b0 trong H\u00ecnh 1-1.<\/p>\n

\"\"

H\u00ecnh 1-1: Bi\u1ec3u \u0111\u1ed3 so s\u00e1nh k\u00edch th\u01b0\u1edbc c\u00e1c lo\u1ea1i vi sinh v\u1eadt<\/p><\/div>\n

 <\/p>\n

\u3010G\u00f3c th\u00f4ng tin th\u00eam\u3011
\n<\/strong>N\u1ebfu l\u1ea5y “1” l\u00e0m m\u1ed1c chu\u1ea9n, c\u00e1c \u0111\u01a1n v\u1ecb c\u00f3 gi\u00e1 tr\u1ecb l\u1edbn h\u01a1n s\u1ebd t\u0103ng d\u1ea7n theo c\u1ea5p s\u1ed1 m\u01b0\u1eddi nh\u01b0: “10”, “100”, “1.000”, “10.000”,… Ng\u01b0\u1ee3c l\u1ea1i, c\u00e1c \u0111\u01a1n v\u1ecb c\u00f3 gi\u00e1 tr\u1ecb nh\u1ecf h\u01a1n s\u1ebd gi\u1ea3m d\u1ea7n theo c\u00e1c ph\u00e2n s\u1ed1: “1\/10”, “1\/1.000”, “1\/10.000”, “1\/100.000” v\u00e0 cu\u1ed1i c\u00f9ng l\u00e0 “1\/1.000.000”.<\/p>\n

 <\/p>\n

\n

 <\/p>\n

T\u00e1c gi\u1ea3<\/strong><\/p>\n

\n
\"\"<\/div>\n
Tatsuo Furuya<\/a>
\nC\u1ed1 v\u1ea5n cao c\u1ea5p, GMP Platform, T\u1eadp \u0111o\u00e0n CM Plus
\nnhi\u1ec1u n\u0103m kinh nghi\u1ec7m chuy\u00ean s\u00e2u trong c\u00e1c l\u0129nh v\u1ef1c qu\u1ea3n l\u00fd ti\u1ec7t tr\u00f9ng, vi sinh h\u1ecdc v\u00e0 \u0111\u1ea3m b\u1ea3o ch\u1ea5t l\u01b0\u1ee3ng (QA) t\u1ea1i c\u00e1c t\u1eadp \u0111o\u00e0n \u0111a qu\u1ed1c gia h\u00e0ng \u0111\u1ea7u nh\u01b0 Johnson & Johnson, Creative Medic v\u00e0 Boston Scientific, tr\u01b0\u1edbc khi ch\u00ednh th\u1ee9c gia nh\u1eadp CM Plus v\u00e0o n\u0103m 2013
\nTrong th\u1eddi gian c\u00f4ng t\u00e1c t\u1ea1i c\u00e1c nh\u00e0 s\u1ea3n xu\u1ea5t thi\u1ebft b\u1ecb y t\u1ebf k\u1ec3 tr\u00ean, v\u1edbi t\u01b0 c\u00e1ch l\u00e0 m\u1ed9t chuy\u00ean gia h\u00e0ng \u0111\u1ea7u v\u1ec1 ph\u01b0\u01a1ng ph\u00e1p ti\u1ec7t tr\u00f9ng b\u1eb1ng kh\u00ed Ethylene Oxide (EO\/EtO), \u00f4ng \u0111\u00e3 t\u00edch c\u1ef1c tham gia v\u00e0o Nh\u00f3m Nghi\u00ean c\u1ee9u Khoa h\u1ecdc thu\u1ed9c B\u1ed9 Y t\u1ebf v\u00e0 Ph\u00fac l\u1ee3i Nh\u1eadt B\u1ea3n, c\u00f9ng nhi\u1ec1u \u1ee7y ban chuy\u00ean m\u00f4n li\u00ean quan \u0111\u1ebfn l\u0129nh v\u1ef1c ti\u1ec7t tr\u00f9ng.<\/div>\n<\/div>\n

 
\nV\u1ec1 GMP Platform<\/strong> (https:\/\/www.gmp-platform.com\/<\/a>)<\/p>\n

\n
\"\"<\/div>\n
GGMP Platform l\u00e0 c\u1ed5ng th\u00f4ng tin \u0111i\u1ec7n t\u1eed mi\u1ec5n ph\u00ed chuy\u00ean v\u1ec1 c\u00e1c ki\u1ebfn th\u1ee9c, quy \u0111\u1ecbnh GMP \u0111\u01b0\u1ee3c th\u00e0nh l\u1eadp v\u00e0o n\u0103m 2012 v\u00e0 v\u1eadn h\u00e0nh b\u1edfi T\u1eadp \u0111o\u00e0n CM Plus (CM Plus Corporation). \u0110\u01b0\u1ee3c x\u00e2y d\u1ef1ng d\u1ef1a tr\u00ean tri\u1ebft l\u00fd c\u1ed1t l\u00f5i c\u1ee7a CM Plus l\u00e0 \u0111\u1ed3ng h\u00e0nh v\u00e0 gi\u1ea3i quy\u1ebft c\u00e1c th\u00e1ch th\u1ee9c li\u00ean quan \u0111\u1ebfn qu\u1ea3n l\u00fd ch\u1ea5t l\u01b0\u1ee3ng t\u1ea1i c\u00e1c c\u01a1 s\u1edf khoa h\u1ecdc \u0111\u1eddi s\u1ed1ng, trang web cung c\u1ea5p nh\u1eefng th\u00f4ng tin mang t\u00ednh th\u1ef1c ti\u1ec5n cao, \u0111\u01b0\u1ee3c d\u1eabn d\u1eaft b\u1edfi \u0111\u1ed9i ng\u0169 chuy\u00ean gia h\u00e0ng \u0111\u1ea7u d\u00e0nh ri\u00eang cho nh\u00e2n s\u1ef1 trong ng\u00e0nh s\u1ea3n xu\u1ea5t khoa h\u1ecdc \u0111\u1eddi s\u1ed1ng. V\u1edbi h\u01a1n 26.000 th\u00e0nh vi\u00ean \u0111\u00e3 \u0111\u0103ng k\u00fd, GMP Platform li\u00ean t\u1ee5c c\u1eadp nh\u1eadt c\u00e1c xu h\u01b0\u1edbng v\u00e0 quy \u0111\u1ecbnh ph\u00e1p l\u00fd m\u1edbi nh\u1ea5t v\u1ec1 GMP t\u1ea1i Nh\u1eadt B\u1ea3n, Hoa K\u1ef3, Ch\u00e2u \u00c2u c\u0169ng nh\u01b0 c\u00e1c khu v\u1ef1c kh\u00e1c. B\u00ean c\u1ea1nh \u0111\u00f3, n\u1ec1n t\u1ea3ng c\u00f2n cung c\u1ea5p c\u00e1c b\u00e0i vi\u1ebft d\u1ecbch thu\u1eadt v\u00e0 gi\u1ea3i ngh\u0129a chuy\u00ean s\u00e2u v\u1ec1 c\u00e1c h\u01b0\u1edbng d\u1eabn (guidelines), b\u00e0i vi\u1ebft k\u1ef9 thu\u1eadt, h\u1ed9i th\u1ea3o chuy\u00ean \u0111\u1ec1, ch\u01b0\u01a1ng tr\u00ecnh \u0111\u00e0o t\u1ea1o tr\u1ef1c tuy\u1ebfn (e-learning) v\u00e0 s\u00e1ch chuy\u00ean ng\u00e0nh. \u0110\u00e2y l\u00e0 chuy\u00ean trang \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i b\u1edfi c\u00e1c chuy\u00ean gia l\u00e0m vi\u1ec7c trong l\u0129nh v\u1ef1c tu\u00e2n th\u1ee7 GMP, \u0111\u1ea3m b\u1ea3o ch\u1ea5t l\u01b0\u1ee3ng (QA) v\u00e0 ph\u00e1t tri\u1ec3n c\u00e1c h\u1ec7 th\u1ed1ng qu\u1ea3n l\u00fd ch\u1ea5t l\u01b0\u1ee3ng hi\u1ec7u qu\u1ea3. Vui l\u00f2ng s\u1eed d\u1ee5ng Google D\u1ecbch ho\u1eb7c c\u00e1c c\u00f4ng c\u1ee5 d\u1ecbch thu\u1eadt t\u01b0\u01a1ng \u0111\u01b0\u01a1ng \u0111\u1ec3 \u0111\u00f3n \u0111\u1ecdc th\u00eam nhi\u1ec1u b\u00e0i vi\u1ebft chuy\u00ean ng\u00e0nh kh\u00e1c v\u1ed1n \u0111\u01b0\u1ee3c xu\u1ea5t b\u1ea3n g\u1ed1c b\u1eb1ng ti\u1ebfng Nh\u1eadt.
\n*N\u1ebfu b\u1ea1n \u0111ang s\u1eed d\u1ee5ng Google Chrome, ch\u1ec9 c\u1ea7n nh\u1ea5p chu\u1ed9t ph\u1ea3i v\u00e0o b\u00e0i vi\u1ebft v\u00e0 ch\u1ecdn “D\u1ecbch sang ti\u1ebfng Vi\u1ec7t” (ho\u1eb7c “Google Translate”).<\/div>\n<\/div>\n","protected":false},"featured_media":6329,"template":"","columncat":[61],"columntag":[],"keywords":[11],"class_list":["post-6221","column","type-column","status-publish","has-post-thumbnail","hentry","columncat-gmp","keywords-gmpgdp"],"acf":[],"yoast_head":"\n\u0110\u1ea1i c\u01b0\u01a1ng v\u1ec1 Vi sinh h\u1ecdc [Ph\u1ea7n 1]\uff5cCM Plus<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cm-plus.co.jp\/vn\/column\/gmp\/2026_0610\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u0110\u1ea1i c\u01b0\u01a1ng v\u1ec1 Vi sinh 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